CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 806 enrolled
Drug / intervention
Knee-length, graduated elastic compression stocking +1 moredevice
Likely dose
Knee-length, graduated elastic compression stocking, 30-40 mm Hg, worn daily for 2 yearsAI-extracted
Key inclusion· 3
  • ✓First, symptomatic, objectively confirmed proximal DVT diagnosed within the last 14 days
  • ✓Able to tolerate standard heparin and/or warfarin treatment
  • ✓Informed consent provided
Key exclusion· 5
  • ✕Contraindication to compression stockings
  • ✕Limited life expectancy (less than 6 months)
  • ✕Cannot return for follow-up visits due to geographic inaccessibility
  • ✕Unable to apply stockings daily or arrange caregiver assistance

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00143598
NCT00143598Phase 3Completed
CompareCT.gov

The SOX Trial: Compression Stockings to Prevent the Post-Thrombotic Syndrome After Symptomatic Proximal Deep Venous Thrombosis

Sir Mortimer B. Davis - Jewish General Hospital·interventional·Posted Sep 2, 2005·Updated Aug 18, 2014

In Brief

A Phase 3 clinical trial evaluating Knee-length, graduated elastic compression stocking and Knee-length, placebo stocking for Deep Venous Thrombosis. Completed, enrolled 806 participants across 25 sites in 2 countries.

Detailed Summary

The purpose of this study is to determine whether elastic compression stockings used for 2 years are effective in preventing the post-thrombotic syndrome in patients with symptomatic proximal deep venous thrombosis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDeep Venous Thrombosis
CountriesCanada, United States
CollaboratorsCanadian Institutes of Health Research (CIHR), Sigvaris Corporation

Timeline

Phase 3CompletedFinished
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 2, 2005
Enrollment StartJun 1, 2004
Primary CompletionFeb 1, 2012
TodayJul 2, 2026
Enrollment to primary: 7.7 yearsPosted 20.8 years ago

Interventions

Knee-length, graduated elastic compression stockingdevice

Worn daily for 2 years, 30-40 mm Hg

Knee-length, placebo stockingdevice

Worn daily for two years