At a glance
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Naltrexone Treatment of Alcohol Abuse in Schizophrenia
In Brief
A Phase 4 clinical trial evaluating Naltrexone or Placebo for Schizophrenia and 4 related conditions. Completed, enrolled 90 participants across 4 sites.
Detailed Summary
The primary purpose of this study is to determine whether naltrexone is effective in the treatment of alcohol dependence and abuse in patients with schizophrenia and schizoaffective disorder. Hypotheses are as follows: hypothesis 1: Naltrexone will be more effective than placebo in reducing alcohol use. hypothesis 2: Patients responding to naltrexone by reducing alcohol use will also show reductions in severity of psychiatric symptoms and utilization of inpatient and emergency psychiatric services. hypothesis 3: Severity of psychiatric symptoms and amount of service utilization will correlate positively with alcohol use.
Study Details
Timeline
Interventions
Naltrexone or Placebo 50 mg per day