At a glance
ClinicalIndex Comparison Record- ✓Established CRT + ICD indications per current guidelines (Class I-IIA)
- ✓Currently implanted with a Medtronic Marquis Family ICD device capable of RV-ATP or BIV-ATP
- ✓For patients with chronic atrial fibrillation: complete AV ablation performed with documented complete AV block at first post-implant device check
- ✕Life expectancy less than 1 year due to non-cardiac chronic disease
- ✕On heart transplant waiting list with expected transplant within 1 year
- ✕Age less than 18 years
- ✕Device replacement or upgrade procedures
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
ADVANCE CRT - D: ATP Delivery for Painless ICD Therapy
In Brief
A Phase 4 clinical trial evaluating Implantable Cardiac Defibrillator for Tachycardia, Ventricular and Ventricular Fibrillation. Completed, enrolled 526 participants across 1 site.
Detailed Summary
To compare the efficacy of RV and BiV ATP for the termination of ventricular arrhythmias in patients who are candidates to a cardiac resynchronisation therapy (CRT) and have a Class I or IIA indication for ICD implantation. The hypothesis of delivering ATP from different sites (RV or BIV) has never been evaluated in a prospective, controlled and randomized study.
Study Details
Timeline
Interventions
Implantable cardiac defibrillator with programmable Fast Ventricular tachycardia detection (FVT) window