CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 43 enrolled
Drug / intervention
Propranolol +1 moredrug
Likely dose
Propranolol short-acting or long-acting capsule (dose not specified)AI-extracted
Key inclusion· 3
  • ✓Experienced an acute psychological traumatic event
  • ✓Heart rate of 80 bpm or greater at enrollment
  • ✓Able to understand English
Key exclusion· 13
  • ✕Traumatic event occurred more than 4 hours before emergency department arrival
  • ✕Physical injury that may affect safe participation, including head injury
  • ✕Systolic blood pressure less than 100 mm Hg
  • ✕Medical or surgical condition posing shock risk

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00158262
NCT00158262Phase 4Completed
CompareCT.gov

Prophylaxis of Posttraumatic Stress Disorder With Post-Trauma Propranolol

Massachusetts General Hospital·interventional·Posted Sep 12, 2005·Updated Apr 10, 2017

In Brief

A Phase 4 clinical trial evaluating Propranolol and Placebo for Post-Traumatic Stress Disorder. Completed, enrolled 43 participants across 2 sites.

Detailed Summary

This study will assess the effectiveness of taking propranolol soon after a traumatizing incident in reducing the incidence and severity of posttraumatic stress disorder in acutely traumatized individuals.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPost-Traumatic Stress Disorder
CountriesUnited States
CollaboratorsNational Institute of Mental Health (NIMH)

Timeline

Phase 4CompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 12, 2005
Enrollment StartSep 1, 2004
Primary CompletionMay 1, 2008
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 20.8 years ago

Interventions

Propranololdrug

Propranolol short-acting or long-acting capsule

Placebodrug

Placebo-matching propranolol short-acting or long-acting capsule