CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 71 target
Drug / intervention
maintained antipsychotic treatment vs. stepwise drug discontinuationother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00159120
NCT00159120Phase 4Completed
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Maintenance Treatment vs. Stepwise Drug Discontinuation After One Year of Maintenance Treatment in First-Episode Schizophrenia

Heinrich-Heine University, Duesseldorf·interventional·Posted Sep 12, 2005·Updated Jan 30, 2008

In Brief

A Phase 4 clinical trial evaluating maintained antipsychotic treatment vs. stepwise drug discontinuation for Schizophrenia and Psychoses. Completed, enrolled 71 participants across 1 site.

Detailed Summary

After one year neuroleptic maintenance treatment in patients with first episode schizophrenia, neuroleptic treatment will be continued vs. stepwise discontinued (randomized design) over a period of 1 year. Under both conditions prodrome based early intervention take place.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSchizophrenia, Psychoses
CountriesGermany
CollaboratorsGerman Federal Ministry of Education and Research, German Research Network On Schizophrenia, Janssen-Cilag Ltd., University of Bonn, Humboldt-Universität zu Berlin, Ludwig-Maximilians - University of Munich, University of Göttingen, University of Cologne, Mainz University, University Hospital Tuebingen, Universität Duisburg-Essen, University of Mannheim, University of Jena, Martin-Luther-Universität Halle-Wittenberg, RWTH Aachen University, University of Wuerzburg

Timeline

Phase 4CompletedFinished
20022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 12, 2005
Enrollment StartNov 1, 2001
Primary CompletionJun 1, 2006
TodayJul 2, 2026
Enrollment to primary: 4.6 yearsPosted 20.8 years ago

Interventions

maintained antipsychotic treatment vs. stepwise drug discontinuationother

maintained antipsychotic treatment (in low dose) vs. stepwise drug discontinuation; both supplemented by prodrome-based early intervention; 1 year