At a glance
ClinicalIndex Comparison Record- ✓Probable medication-overuse headache according to ICHD-2 criteria (section 8.2.7)
- ✕No benefit from all available preventive medications
- ✕No benefit from abrupt withdrawal of overused acute medication lasting more than 3 weeks
- ✕Cluster headache
- ✕Chronic paroxysmal hemicrania
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Medication-overuse Headache (MOH): Withdrawal or Use of Preventative Medications Directly? A Randomized Multi-centre Follow-up.
In Brief
A clinical study evaluating Betablockers or other preventive drugs based on primary headache type for Headache. Completed, enrolled 64 participants across 1 site.
Detailed Summary
It is a common belief that patients with MOH rarely respond of preventative medications whilst overusing acute medications. However, no randomized trial has been done previously to prove such statement. Based on some clinical experiences, our hypothesis are patients with probably MOH may benefit from use of preventive medications better than treatment with abrupt withdrawal or no specific treatment.
Study Details
Timeline
Interventions
Several preventive drugs based on each individual regarding type of original headache type (i.e angiotensin II blockers, betablockers, valproate, tricyclic antidepressants or gabapentin)