At a glance
ClinicalIndex Comparison Record- ✓Age 6-18 years old
- ✓Established history of insulin dependent diabetes
- ✓Presenting with hyperglycemia or vomiting
- ✓Venous pH < 7.24
- ✕Age < 6 years old
- ✕New onset diabetes (not established)
- ✕Received IV insulin bolus prior to arrival at emergency room
- ✕Venous pH > 7.24 (insufficient acidosis for DKA diagnosis)
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Early Use of Insulin Glargine in Diabetic Ketoacidosis
In Brief
A clinical study evaluating glargine and saline for Diabetic Ketoacidosis. Completed, enrolled 75 participants across 1 site.
Detailed Summary
The purpose of this study is to determine the effects of the addition of insulin glargine during the early phase of moderate to severe Diabetic Ketoacidosis (DKA) in children. The investigators hypothesize that the addition of insulin glargine during the early phase of management of DKA will accelerate acidosis correction, decrease the length of insulin infusion, and decrease the total intensive care unit time in children admitted to the ICU.
Study Details
Timeline
Interventions
0.3u/kg of glargine, subcutaneously, once
0.3u/kg of saline, subcutaneously, once