CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 80 enrolled
Drug / intervention
Nebulised Bupivacaine intraperitoneally +3 moredrug
Likely dose
Bupivacaine nebulised intraperitoneally (specific dose not stated)AI-extracted
Key inclusion· 1
  • Patients undergoing laparoscopic cholecystectomy
Key exclusion· 3
  • Local anesthetic allergy
  • Chronic opioid medication use
  • Neurological diseases that impair pain evaluation

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00180687
NCT00180687Phase 3Completed

Prospective Double Blind Randomized Controlled Trial of the Use of Intraperitoneal Nebulised Local Anaesthetic

Imperial College London·interventional·Posted Sep 16, 2005·Updated Sep 15, 2015

In Brief

A Phase 3 clinical trial evaluating Nebulised Bupivacaine intraperitoneally, Normal Saline, and 2 other interventions for Pain, Postoperative. Completed, enrolled 80 participants across 1 site.

Detailed Summary

Patients undergoing keyhole gall bladder removal will be divided into 3 groups, one control, one will have local anaesthetic and the third will have normal saline nebulised into their abdomen before closure of the wounds to reduce postoperative pain. These medications will be given on top of the standard pain management protocol.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom
Collaborators--

Timeline

Phase 3CompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 16, 2005
Enrollment StartOct 1, 2004
Primary CompletionSep 1, 2005
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 20.8 years ago

Interventions

Nebulised Bupivacaine intraperitoneallydrug

Nebulised Marcaine (Bupivacaine)

Normal Salinedrug

Nebulised Normal Saline

Injected Bupivacaine intraperitoneallydrug

Injected Marcaine directly into the peritoneal cavity

No Intraperitoneal Therapeuticsother

No Intraperitoneal Therapeutics given