CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 11 enrolled
Drug / intervention
Recombinant Human Prolactin +2 moredrug
Likely dose
60 mcg/kg intravenously every 12 or 24 hoursAI-extracted
Key inclusion· 4
  • Healthy women aged 18–45 years
  • Lactation insufficiency postpartum
  • Mothers pumping breast milk for premature infants in the NICU
  • Given birth at ≥24 weeks gestation, recruited 4–8 weeks postpartum
Key exclusion· 6
  • Medications known to increase prolactin
  • Anatomical breast abnormalities
  • Medications contraindicated in breastfeeding mothers
  • Allergy to mannitol

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00181610
NCT00181610Phase 2Completed

Recombinant Human Prolactin for Lactation Induction in Mothers of Premature Infants

Massachusetts General Hospital·interventional·Posted Sep 16, 2005·Updated Jan 3, 2018

In Brief

A Phase 2 clinical trial evaluating Recombinant Human Prolactin, Recombinant human prolactin, and 1 other intervention for Lactation. Completed, enrolled 11 participants across 1 site.

Detailed Summary

The purpose of the study is to assess the safety and determine the effects of the hormone prolactin on lactation (breast milk production).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLactation
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 16, 2005
Enrollment StartSep 1, 2004
Primary CompletionSep 1, 2010
TodayJul 2, 2026
Enrollment to primary: 6 yearsPosted 20.8 years ago

Interventions

Recombinant Human Prolactindrug

60 mcg/kg every 12 hours

Recombinant human prolactinbiological

60 mcg/kg given every 12 hours or every 24 hours

Normal Salinebiological

twice per day