At a glance
ClinicalIndex Comparison RecordPhase 4Completed
Drug / intervention
Donepezildrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Preventing Post-Operative Cognitive Decline
In Brief
A Phase 4 clinical trial evaluating Donepezil for Postoperative Complications and Delirium. Completed, across 1 site.
Detailed Summary
The purpose of this study is to evaluate the feasibility of using Donepezil to prevent post-operative cognitive decline (POCD) among individuals aged 65 and older who have a baseline mild cognitive impairment (MCI) and are undergoing elective hip or knee replacement.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPostoperative Complications, Delirium
CountriesUnited States
Collaborators--
Timeline
Phase 4CompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartFeb 2005
First PostedSep 2005
Primary CompletionApr 2007
TodayJul 2026
First PostedSep 16, 2005
Enrollment StartFeb 1, 2005
Primary CompletionApr 1, 2007
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 20.8 years ago
Interventions
Donepezildrug