At a glance

ClinicalIndex Comparison Record

Phase 4Completed· 184 enrolled

Drug / intervention

Antidepressants +2 moredrug

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00183560

NCT00183560Phase 4Completed

Compare CT.gov

Prevention of Relapse in Recurrent Depression With MBCT

Centre for Addiction and Mental Health·interventional·Posted Sep 16, 2005·Updated Jul 1, 2015

In Brief

A Phase 4 clinical trial evaluating Mindfulness based cognitive therapy (MBCT), Antidepressants, and 1 other intervention for Depression. Completed, enrolled 184 participants across 2 sites.

Detailed Summary

This study will determine the effectiveness of mindfulness-based cognitive therapy (MBCT) in preventing depression relapse.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsDepression

CountriesCanada

CollaboratorsNational Institute of Mental Health (NIMH)

Timeline

Phase 4CompletedFinished

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027

Enrollment StartJul 2004

First PostedSep 2005

Primary CompletionOct 2010

TodayJul 2026

First PostedSep 16, 2005

Enrollment StartJul 1, 2004

Primary CompletionOct 1, 2010

TodayJul 2, 2026

Enrollment to primary: 6.3 yearsPosted 20.8 years ago

Interventions

Mindfulness based cognitive therapy (MBCT)behavioral

Following antidepressant discontinuation, participants receive MBCT, an 8-week group program that integrates aspects of cognitive therapy and mindfulness meditation.

Antidepressantsdrug

Participants continue on dosage of the antidepressant that was used to achieve clinical remission.

Placebo plus clinical managementdrug

Following discontinuation of active antidepressant, participants are placed onto the placebo and clinical management regimen.