At a glance
ClinicalIndex Comparison RecordN/ACompleted· 10 enrolled
Drug / intervention
Hydrocortisone Administration (Standard of Care Therapy)drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Pilot Study of White Blood Cell Gene Expression in Critically Ill Patients With Severe Sepsis and Relative Adrenal Insufficiency After Hydrocortisone Administration
In Brief
An observational study evaluating Hydrocortisone Administration (Standard of Care Therapy) for Sepsis and Relative Adrenal Insufficiency. Completed, enrolled 10 participants across 1 site.
Detailed Summary
The purpose of this pilot study is to (1) examine the changes in gene expression in patients who suffer from severe sepsis and whose shock (inadequate oxygen delivery to vital organs) state does not respond to fluid and vasopressor administration, (2) to show that our sampling method of isolating RNA provides reliable and consistent data, (3) provide a basis for future gene expression studies in critically ill patients
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsSepsis, Relative Adrenal Insufficiency
CountriesUnited States
CollaboratorsUniversity of Toronto, University of Colorado, Denver
Timeline
N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartMar 2005
First PostedSep 2005
Primary CompletionNov 2006
TodayJul 2026
First PostedSep 16, 2005
Enrollment StartMar 1, 2005
Primary CompletionNov 1, 2006
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 20.8 years ago
Interventions
Hydrocortisone Administration (Standard of Care Therapy)drug