CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Magnesium Sulfate +1 moredrug
Likely dose
Magnesium Sulfate 4 gram bolus, followed by 2 grams per hour maintenance (up to 4 grams per hour)AI-extracted
Key inclusion· 2
  • ✓Vaginal bleeding and contractions consistent with suspected placental abruption
  • ✓Gestational age between 24 and 34 weeks
Key exclusion· 4
  • ✕Preterm labor
  • ✕Severe bleeding necessitating immediate delivery
  • ✕Maternal coagulopathy
  • ✕Fetal distress

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00186069
NCT00186069N/ACompleted
CompareCT.gov

Randomized, Double Blind Trial of Magnesium Sulfate Tocolysis Versus Intravenous Saline for Suspected Placental Abruption

Stanford University·interventional·Posted Sep 16, 2005·Updated Jan 2, 2018

In Brief

A clinical study evaluating Magnesium Sulfate and Normal Saline for Abruptio Placentae. Completed, enrolled 30 participants across 2 sites.

Detailed Summary

To evaluate the safety and efficacy of magnesium sulfate for preterm suspected abruption.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAbruptio Placentae
CountriesUnited States
CollaboratorsSanta Clara Valley Medical Center

Timeline

N/ACompletedFinished
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 16, 2005
Enrollment StartMar 1, 2004
Primary CompletionJun 1, 2014
Study CompletionNov 1, 2017
TodayJul 2, 2026
Enrollment to primary: 10.3 yearsPosted 20.8 years ago

Interventions

Magnesium Sulfatedrug

Magnesium Sulfate 4 gram bolus, followed by a maintenance dose at 2 grams per hour. Rate increases up to 4 grams per hour may be administered per physician discretion.

Normal Salineother

Normal Saline infusion of 4 gram bolus, followed by 2 grams per hour with rate increases up to 4 grams per hour per physician discretion.