CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed
Drug / intervention
Engerix-B and Twinrixbiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00186836
NCT00186836Phase 4Completed
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Efficacy of Combined Hepatitis A and Hepatitis B (Twinrix) Vaccine Compared With Hepatitis B Vaccine Alone in Providing Seroprotection Against Hepatitis B in Hemodialysis Patients

St. Joseph's Health Care London·interventional·Posted Sep 16, 2005·Updated Apr 20, 2007

In Brief

A Phase 4 clinical trial evaluating Engerix-B and Twinrix for Hepatitis B. Completed, across 1 site.

Detailed Summary

Does vaccinating hemodialysis patients with Twinrix® (combination vaccine against hepatitis A and hepatitis B) result in a difference in hepatitis B antibody response in comparison to the monovalent hepatitis B vaccine? Hepatitis B infection is an important cause of mortality and morbidity. Current standard vaccination practices have low efficacy levels in patients (eg. hemodialysis patients) who are most susceptible of infection. Efficacy of the two regiments will be studied.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHepatitis B
CountriesCanada
Collaborators--

Timeline

Phase 4CompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 16, 2005
Enrollment StartNov 1, 2004
Study CompletionNov 1, 2006
TodayJul 2, 2026
Posted 20.8 years ago

Interventions

Engerix-B and Twinrixbiological