CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 202 enrolled
Drug / intervention
image-guided radiotherapyradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00186992
NCT00186992Phase 2Active

Image Guided Radiotherapy for the Treatment of Musculoskeletal Tumors: A Phase II Prospective Evaluation of Radiation-related Treatment Effects

St. Jude Children's Research Hospital·interventional·Posted Sep 16, 2005·Updated Mar 4, 2026

In Brief

A Phase 2 clinical trial evaluating image-guided radiotherapy for Sarcoma, Ewing's and 3 related conditions. Active but no longer recruiting, targeting 202 participants across 1 site.

Detailed Summary

Researchers at St. Jude Children's Research Hospital are looking for more effective ways to deliver radiation therapy to pediatric tumors of the bone and soft tissues. The goal of the study is to improve local control of musculoskeletal tumors with image-guided radiation therapy (IGRT) while minimizing radiation related side effects. IGRT uses computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) images to precisely define tumor location and to carefully plan radiation treatment. This approach allows doctors to deliver highly conformal radiation therapy to the tumor while protecting nearby healthy normal tissues.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2Active
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027202820292030
First PostedSep 16, 2005
Enrollment StartJan 10, 2003
Primary CompletionSep 15, 2023
Study CompletionOct 1, 2029
TodayJul 2, 2026
Enrollment to primary: 20.7 yearsPosted 20.8 years ago

Interventions

image-guided radiotherapyradiation

Conformal limited image radiotherapy is radiation therapy that targets tumors with a prescribed dose of radiation which allows the surrounding normal tissues to remain basically untreated.