At a glance
ClinicalIndex Comparison RecordN/ACompleted· 24 enrolled
Drug / intervention
Mycophenolate mofetil + Tacrolimus +1 moredrug
Likely dose
Mycophenolate mofetil + Tacrolimus 60 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Pilot Trial for Implementation of a MPA PK Monitoring Strategy
In Brief
A clinical study evaluating Mycophenolate mofetil + Tacrolimus and Mycophenolate mofetil + Cyclosporin for Transplant, Kidney. Completed, enrolled 24 participants across 1 site.
Detailed Summary
This study is a prospective interventional trial of de novo renal transplant recipients, aiming to validate a strategy which combines the use of early post transplant MPA AUC sampling, and subsequent MPA trough level monitoring to implement MPA PK monitoring in a clinically applicable fashion.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTransplant, Kidney
CountriesUnited States
CollaboratorsHoffmann-La Roche
Timeline
N/ACompletedFinished
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartJul 2003
Primary CompletionNov 2004
Study CompletionDec 2004
First PostedSep 2005
TodayJul 2026
First PostedSep 16, 2005
Enrollment StartJul 1, 2003
Primary CompletionNov 1, 2004
Study CompletionDec 1, 2004
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 20.8 years ago
Interventions
Mycophenolate mofetil + Tacrolimusdrug
Target MPA exposure to 30-60 mg/L/h during first month post-transplant
Mycophenolate mofetil + Cyclosporindrug
Target MPA exposure to 30-60 mg/L/h during first month post-transplant