At a glance
ClinicalIndex Comparison Record- ✓Nonpregnant females
- ✓Good general health
- ✓Symptoms of acute cystitis
- ✓Regularly contracepting (if of childbearing potential)
- ✕Pregnant or lactating
- ✕Known anatomic abnormalities of the urinary tract
- ✕Use of prophylactic antibiotics
- ✕History of allergy or intolerance to cefpodoxime or ciprofloxacin
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Cefpodoxime vs Ciprofloxacin for Acute Cystitis
In Brief
A clinical study evaluating Cefpodoxime and Ciprofloxacin for Urinary Tract Infection. Completed, enrolled 300 participants across 2 sites.
Detailed Summary
Urinary tract infection (UTI) is a very common problem in young healthy women, afflicting approximately one-half of women by their late 20s. One of the most common antibiotics used to treat UTIs is ciprofloxacin, usually for a total of three days. However, increasing resistance to this antibiotic has raised concerns about its overuse for cystitis and generated interest in alternative agents. An alternative antibiotic which is approved for use in UTIs is cefpodoxime. However, there are few studies evaluating the efficacy and tolerance of this compound when given in a 3-day regimen as is commonly used for treatment of UTI. The major purpose of this study is to assess the efficacy and tolerance of a 3-day regimen of cefpodoxime versus ciprofloxacin for treatment of acute uncomplicated cystitis.
Study Details
Timeline
Interventions
Cefpodoxime 100mg twice a day(BID)for 3 days
Ciprofloxacin 250mg twice a day (BID)for 3 days