CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,014 enrolled
Drug / intervention
Etanerceptdrug
Likely dose
Etanercept 25 mg injection, 2 times per weekAI-extracted
Key inclusion· 3
  • Adults with active RA and inadequate response to DMARDs including methotrexate
  • Children aged 4-17 years with polyarticular-course chronic active RA with inadequate response to or intolerance of methotrexate
  • Adults with active and progressive psoriatic arthritis unresponsive to previous DMARDs
Key exclusion· 4
  • Patients with known hypersensitivity to Etanercept or any component of the product
  • Patients with sepsis or risk of sepsis
  • Patients with active infections including chronic or localized infections such as tuberculosis
  • Patients to whom Enbrel is contraindicated per local labeling

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00195403
NCT00195403N/ACompleted

A Drug Use Investigation of Enbrel for Post-Marketing Surveillance

Pfizer·observational·Posted Sep 19, 2005·Updated Aug 15, 2013

In Brief

An observational study evaluating Etanercept for Rheumatoid Arthritis. Completed, enrolled 1,014 participants across 4 sites.

Detailed Summary

The objective of this investigation is to identify the following problems and questions with respect to the safety and efficacy of Enbrel during the post-marketing period as required by Korea Food and Drug Administration (KFDA)'s regulation. 1. Unknown adverse reactions, especially serious adverse reactions 2. Incidences of adverse reactions under routine drug uses 3. Factors that may affect the safety of the drug 4. Factors that may affect the efficacy of the drug This investigation spanned 3 different studies, 0881A-101575 (alias B1801105) NCT00195403, 0881A-102018 (alias B1801112) NCT00195416 and 0881A-102212 (alias B1801113). All studies have been combined into this record.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesSouth Korea
Collaborators--

Timeline

N/ACompletedFinished
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 19, 2005
Enrollment StartMay 1, 2004
Primary CompletionFeb 1, 2008
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 20.8 years ago

Interventions

Etanerceptdrug

Etanercept 25mg Injection, 2 times/week