CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 9 enrolled
Drug / intervention
garlic powder added to ambient water +1 moredietary
Likely dose
Garlic powder 2.7 grams once daily for 4 weeks (equivalent to 8 grams fresh garlic or cooked garlic depending on preparation method)AI-extracted
Key inclusion· 5
  • Body mass index between 19 and 30 kg/m²
  • Plans to remain in the study area for the next year
  • Willingness to abstain from NSAIDs for 1 week prior to each study test
  • Willingness to abstain from garlic, significant amounts of onion, chocolate, or purple grape juice for 3 days prior to each study test
Key exclusion· 6
  • Pregnancy or breast-feeding
  • Serious medical condition
  • Allergy to garlic or wheat
  • Tobacco use

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00200785
NCT00200785N/ACompleted

Identification of the Antiplatelet Compounds of Garlic Ex Vivo

National Center for Complementary and Integrative Health (NCCIH)·interventional·Posted Sep 20, 2005·Updated Jan 11, 2010

In Brief

A clinical study evaluating garlic powder added to ambient water and garlic powder added to boiling water for Arteriosclerosis and Intracranial Arteriosclerosis. Completed, enrolled 9 participants across 1 site.

Detailed Summary

This study will seek to identify the compound(s) in garlic that is (are) responsible for its ability to prevent the formation of blood clots (prevent platelet aggregation) and to determine the maximally effective dose and duration of the benefits. This study will also determine whether "cooked" garlic (garlic powder added to boiling water, no allicin present) is as effective as "fresh" garlic (garlic powder added to ambient water, high allicin present) and, if more than one compound is involved, and whether their combined effects are more significant than the effects of each compound alone.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 20, 2005
Enrollment StartMar 1, 2006
Primary CompletionSep 1, 2007
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 20.8 years ago

Interventions

garlic powder added to ambient waterdietary

consumed 2.7 grams of garlic powder added to ambient water (equivalent to 8 grams fresh or raw garlic) in a sandwich, once a day for four weeks

garlic powder added to boiling waterdietary

consumed 2.7 grams of garlic powder added to boiling water (equivalent to 8 grams of cooked garlic) in a sandwich, once a day for four weeks