CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 45 enrolled
Drug / intervention
lidocaine, bupivicaine and saline +1 moredrug
Likely dose
Lidocaine and bupivacaine 2 cc injected to each GON with 0.5 cc to each trigger point (total 10 cc); triamcinolone steroid added in experimental armAI-extracted
Key inclusion· 4
  • Age 18-65 years inclusive
  • Chronic daily headache of 15 or more days per month for at least 3 months prior to enrollment
  • Headache severity at least 5/10 at time of GON block
  • Posterior cervical muscle tenderness at time of nerve block
Key exclusion· 7
  • Prior surgery or invasive procedure in the occipital area
  • Abnormal sensory findings or known neurological disease affecting skin sensation (peripheral neuropathy, multiple sclerosis, stroke)
  • Cluster headache diagnosis
  • Skin diseases that may affect skin sensation

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00203294
NCT00203294N/ACompleted

Comparison Of Greater Occipital Nerve Block With Lidocaine And Bupivicaine Alone Or With Steroids In a Chronic Headache Population

Thomas Jefferson University·interventional·Posted Sep 20, 2005·Updated May 7, 2014

In Brief

A clinical study evaluating lidocaine, bupivicaine and saline and lidocaine plus bupivicaine plus triamcinolone (steroid) for Migraine. Completed, enrolled 45 participants across 1 site.

Detailed Summary

Subjects are scheduled to undergo a Greater Occipital Nerve Block (GONB) as treatment for your chronic daily headache (CDH). GONB has been used for many years in the treatment of headaches. The nerve block is done by injecting a liquid drug through the skin of the back of the head to the area of the greater occipital nerve. The nerve runs superficially in this area, therefore the drugs are injected just under the skin. The injected drugs block electrical transmission through the nerve, resulting in reduced head pain. There are treatment options for patients receiving a GONB, however, some clinicians use local anesthetics (lidocaine and /or bupivicaine) alone, and some use local anesthetics with local steroid injection. The purpose of this study is to evaluate whether or not there is an observed difference between these two treatment approaches for GONB. We expect to enroll 60 patients into this research study at Thomas Jefferson University only.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMigraine
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 20, 2005
Enrollment StartJun 1, 2005
Primary CompletionJun 1, 2006
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 20.8 years ago

Interventions

lidocaine, bupivicaine and salinedrug

lidocaine, bupivicaine and saline-2 cc were injected to each GON and 0.5 cc to each trigger point. Total injected volume = 10 cc.

lidocaine plus bupivicaine plus triamcinolone (steroid)drug

lidocaine, bupivicaine and triamcinolone (steroid)-2 cc were injected to each GON and 0.5 cc to each trigger point. Total injected volume = 10 cc.