At a glance
ClinicalIndex Comparison Record- ✓Healthy premenopausal women
- ✓Age 30-42 years
- ✓Normal mammograms
- ✓Regular menstrual cycles
- ✕Abnormal mammograms
- ✕First-degree relatives with breast cancer
- ✕Pregnant or lactating
- ✕Peri- or post-menopausal status
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Mammographic Density and Soy Isoflavones
In Brief
A Phase 2 clinical trial evaluating isoflavones and carbohydrate for Breast Cancer. Completed, enrolled 197 participants across 1 site.
Detailed Summary
Soy consumption has been associated with reduced risk for developing breast cancer. Soy contains isoflavones which are weak estrogens. The roles of soy isoflavones in reducing breast cancer risk are currently unclear. Breast density has been considered as a breast cancer risk marker. We hypothesize that because isoflavones have estrogen-like activities, breast density and possibly bone density will be lower in women on soy-isoflavones.
Study Details
Timeline
Interventions
soy isoflavones: Each tablet contains 246 mg Novasoy, 676 mg calcium, 15 mg riboflavin, and other innert materials to a total weight of 1000 mg. Subject takes two isoflavone tablets plus 1 multi-vitamin per day for five days per week for upto 2 years.
carbohydrate: 246 mg maltodextrin, 676 mg calcium, 15 mg riboflavin and other innert ingredients to a total weight of 1000 mg per tablet. subject takes two tablets plus one multivitamin per day for five days per week for upto 2 years.