At a glance
ClinicalIndex Comparison Record- ✓BMI 25-29.9 kg/m²
- ✓Stable weight (no change >3 kg in previous 6 months)
- ✕Current or recent (≤6 months) enrollment in a weight loss program (commercial or self-prescribed)
- ✕Physical limitation that prevents walking exercise
- ✕History of metabolic disease (renal, endocrine, hepatic, or gastrointestinal) that would impact study outcome
- ✕History of psychiatric or eating disorders
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effects of CLA Supplements on Body Weight and Fat Oxidation
In Brief
A Phase 2 clinical trial evaluating conjugated linoleic acid for Obesity. Completed, enrolled 53 participants across 1 site.
Detailed Summary
Conjugated linoleic acid (CLA) is form of fat found in dairy foods, beef and other natural sources. When given to small animals, decreases of body fat have been noted.. Although weight loss is the best treatment for overweight and obesity, it is difficult to maintain the loss in the long term. Because of this, treatment emphasis has turned to small weight losses obtained through non-restrictive diets and prevention of weight regain. This is a study to determine if 6 months of consumption a purified form of CLA will result in greater loss of body fat than control and to determine whether CLA consumption increases total fat oxidation, which would help explain why the weight loss occurs.
Study Details
Timeline
Interventions
4 grams per day of 39% cis-9, trans-11 CLA; 39% trans-10, cis-12 CLA, and 22% safflower oil for 6 months