CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 230 enrolled
Drug / intervention
Ketamine +1 moredrug
Likely dose
Not stated in record
Key inclusion· 3
  • ✓Age 18 years or older
  • ✓ASA physical status class 1 or 2
  • ✓Undergoing breast cancer surgery (mastectomy or tumorectomy)
Key exclusion· 6
  • ✕Ketamine hypersensitivity
  • ✕Major psychiatric disorders
  • ✕Major cardiovascular disorders
  • ✕Major neurologic disorders

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00210210
NCT00210210Phase 3Completed
CompareCT.gov

Effect of Ketamine, at the Induction and Its Maintenance to Prevent the Post-operative Pain: Clinical Trial in Cancerology

Institut Bergonié·interventional·Posted Sep 21, 2005·Updated Sep 19, 2025

In Brief

A Phase 3 clinical trial evaluating Ketamine and Saline solution for Postoperative Pain and Breast Cancer. Completed, enrolled 230 participants across 1 site.

Detailed Summary

The surgery of breast cancer is responsible for post-operative pain, needing in about 30% some morphine consumption; like that, the association of ketamine with general anaesthesia may decrease morphine's use and so its adverse effects. The purpose is to evaluate the analgesic effect of a receptor NMDA's antagonist ( ketamine)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPostoperative Pain, Breast Cancer
CountriesFrance
Collaborators--

Timeline

Phase 3CompletedFinished
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 21, 2005
Enrollment StartJan 31, 2004
Primary CompletionJul 31, 2005
Study CompletionDec 31, 2005
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 20.8 years ago

Interventions

Ketaminedrug

Saline solutiondrug