At a glance
ClinicalIndex Comparison Record- ✓Visually significant unilateral congenital cataract with central opacity ≥3 mm
- ✓Cataract surgery performed between 28–210 postnatal days at ≥41 post-conceptional weeks
- ✕Cataract known to be acquired from trauma or postnatal treatment (radiation, medical therapy)
- ✕Corneal diameter <9 mm in horizontal meridian
- ✕Intraocular pressure ≥25 mmHg in affected eye
- ✕Persistent fetal vasculature causing ciliary stretching or tractional retinal detachment
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Infant Aphakia Treatment Study (IATS)
In Brief
A clinical study evaluating Contact lens correction of aphakia and Intraocular lens implantation for Congenital Cataract. Completed, enrolled 114 participants across 13 sites.
Detailed Summary
The primary purpose is to determine whether infants with a unilateral congenital cataract are more likely to develop better vision following cataract extraction surgery if they undergo primary implantation of an intraocular lens or if they are treated primarily with a contact lens. In addition, the study will compare the occurrence of postoperative complications and the degree of parental stress between the two treatments.
Study Details
Timeline
Interventions
optical correction of infant surgical aphakia with Contact lens
optical correction of surgical aphakia with intraocular lens