At a glance
ClinicalIndex Comparison Record- ✓Diagnosed hemato-oncological disorder (hematologic disease or malignancy)
- ✓Scheduled to undergo lumbar puncture
- ✓Age 4–11 years
- ✓No premedication prior to enrollment
- ✕Known or suspected difficult airway (difficult to ventilate by face mask)
- ✕Medically unfit to receive propofol or remifentanil
- ✕Obesity (weight for height >95th percentile)
- ✕No indwelling intravenous line
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The Minimum Effective Dose of Remifentanil When Co-administered With Propofol for Lumbar Puncture in Children: A Dose-finding Study
In Brief
A Phase 2 clinical trial evaluating Remifentanil for Hematologic Diseases and Neoplasms. Completed, enrolled 64 participants across 1 site.
Detailed Summary
This study will examine whether the combination of two anaesthetic medications, propofol and remifentanil, is suitable for short duration surgical procedures, providing a shorter recovery time and fewer side effects than either drug used alone.
Study Details
Timeline
Interventions
The first patient in this group will receive 4 mg/kg propofol and 0.5 ug/kg respectively. The dose of remifentanil in subsequent patients will be determined by the Dixon up-and-down method.
The first patient in this group will receive 2 mg/kg propofol and 1.0 ug/kg respectively. The dose of remifentanil in subsequent patients will be determined by the Dixon up-and-down method.