CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 36 enrolled
Drug / intervention
Lexapro (escitalopram)drug
Likely dose
Not stated in record
Key inclusion· 3
  • ✓Age 18–65 years, male or female outpatients
  • ✓DSM-IV diagnosis of dysthymic disorder
  • ✓Hamilton Depression Scale (24-item) total score ≥12 at baseline
Key exclusion· 9
  • ✕DSM-IV diagnosis of delirium, dementia, amnestic, or other cognitive disorders
  • ✕Current Major Depressive Disorder, Bipolar Disorder, cyclothymia, schizophrenia, delusional or psychotic disorders
  • ✕Anorexia Nervosa or Bulimia Nervosa
  • ✕Substance abuse or dependence within past 6 months (excluding caffeine and tobacco)

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00220701
NCT00220701Phase 4Completed
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Double-Blind Placebo-Controlled Study of Escitalopram in the Treatment of Dysthymic Disorder

St. Luke's-Roosevelt Hospital Center·interventional·Posted Sep 22, 2005·Updated Nov 11, 2015

In Brief

A Phase 4 clinical trial evaluating Lexapro (escitalopram) for Dysthymic Disorder. Completed, enrolled 36 participants across 1 site.

Detailed Summary

This is a 12-week double-blind placebo-controlled study of Escitalopram in treatment of dysthymic Disorder (low-grade chronic depression), with a 12 week open-label extension phase. It is hypothesized that Escitalopram will be superior to placebo in improving depression, as well as psychosocial, temperamental, and cognitive functioning.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDysthymic Disorder
CountriesUnited States
CollaboratorsForest Laboratories

Timeline

Phase 4CompletedFinished
20022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 22, 2005
Enrollment StartJun 1, 2002
Primary CompletionNov 1, 2008
Study CompletionJan 1, 2009
TodayJul 2, 2026
Enrollment to primary: 6.4 yearsPosted 20.8 years ago

Interventions

Lexapro (escitalopram)drug

antidepressant drug selective serotonin reuptake inhibitor (SSRI)