CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 525 enrolled
Drug / intervention
Antiplatelet Agents +3 moredrug
Likely dose
Aspirin 81 mg orally once daily; Beta Blocker (dose not specified); ACE Inhibitor 1-2 times daily (specific dose not specified)AI-extracted
Key inclusion· 5
  • African American or Caucasian with diagnosed CVD (prior MI, revascularization, ischemic heart disease, stroke) or type 2 diabetes not on therapy
  • Currently receiving medical care at Johns Hopkins University
  • LDL cholesterol ≥100 mg/dL on or off lipid-lowering therapy, or no LDL-C recorded in past 12 months
  • Blood pressure >140/90 mmHg (or >130/80 if diabetic/renal insufficiency), or no BP recorded in past 12 months
Key exclusion· 3
  • Life-threatening non-cardiac comorbidity with life expectancy <5 years
  • Serious physician-recorded psychiatric disorder interfering with study participation
  • Significant neurological impairment interfering with study participation

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00241904
NCT00241904Phase 4Completed

Reducing Total Cardiovascular Risk in an Urban Community

Johns Hopkins University·interventional·Posted Oct 19, 2005·Updated Sep 15, 2017

In Brief

A Phase 4 clinical trial evaluating Lifestyle Changes, Antiplatelet Agents, and 2 other interventions for Cardiovascular Diseases and 6 related conditions. Completed, enrolled 525 participants across 1 site.

Detailed Summary

PLEASE NOTE: THIS STUDY IS ONLY ENROLLING PATIENTS CURRENTLY BEING TREATED AT BELAIR-EDISON FAMILY HEALTH CENTER. The purpose of this study is to compare the clinical effectiveness and cost effectiveness of two cardiovascular risk reduction programs - a comprehensive intensive (Cl) intervention with a less intensive (LI) intervention - in African American, and white low-income patients with known excessive cardiovascular disease risk.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 4CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 19, 2005
Enrollment StartMay 1, 2006
Primary CompletionMay 1, 2010
TodayJul 2, 2026
Enrollment to primary: 4 yearsPosted 20.7 years ago

Interventions

Lifestyle Changesbehavioral

Nutrition counseling, smoking cessation counseling, medication compliance counseling, exercise

Antiplatelet Agentsdrug

Aspirin 81 mg q day

Beta Blockerdrug

Oral medication

ACE Inhibitorsdrug

Oral medications, received 1-2 times per day