CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 22 enrolled
Drug / intervention
Namendadrug
Likely dose
Not stated in record
Key inclusion· 5
  • Women aged 50-65 years
  • Personal or family history of mood disorder
  • Hypothyroidism
  • Diabetes
Key exclusion· 8
  • Possible or probable Alzheimer's disease or dementia
  • History of cerebrovascular disease
  • History of myocardial infarction within the previous year
  • History of unstable heart disease

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00242632
NCT00242632N/ACompleted

Cognitive Effects of Memantine in Postmenopausal Women at Risk of Dementia: a Pilot Study

Stanford University·interventional·Posted Oct 20, 2005·Updated Jun 14, 2017

In Brief

A clinical study evaluating Namenda for Dementia. Completed, enrolled 22 participants across 1 site.

Detailed Summary

This research aims to explore the effectiveness of memantine (Namenda) in treating post-menopausal women between the ages of 50 and 65, who are at risk for cognitive decline. Memantine has already been shown to offer cognitive benefits to patients suffering from Alzheimer's disease, but it's potential for treating those at risk for cognitive decline without Alzheimer's disease or other dementia has yet to be evaluated. It is possible that memantine may offer neurocognitive benefits to this population, as well. Participants are asked to take medication for six months, complete neuropsychological testing, and one blood draw.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDementia
CountriesUnited States
CollaboratorsForest Laboratories

Timeline

N/ACompletedFinished
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 20, 2005
Enrollment StartJun 1, 2004
Primary CompletionDec 1, 2009
TodayJul 2, 2026
Enrollment to primary: 5.5 yearsPosted 20.7 years ago

Interventions

Namendadrug

Namenda has already been shown to offer cognitive benefits to patients suffering from Alzheimer's disease, but it's potential for treating those at risk for cognitive decline without Alzheimer's disease or other dementia has yet to be evaluated. It is possible that memantine may offer neurocognitive benefits to this population, as well. Participants are asked to take medication for six months, complete neuropsychological testing, and one blood draw.