CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 812 enrolled
Drug / intervention
Efavirenz +6 moredrug
Likely dose
Efavirenz 600 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00255840
NCT00255840N/ACompleted
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"Safeguard the Household" - A Study of HIV Antiretroviral Therapy Treatment Strategies Appropriate for a Resource Poor Country

CIPRA SA·interventional·Posted Nov 21, 2005·Updated Jun 21, 2011

In Brief

A clinical study evaluating Monitoring by an HIV-trained medical doctor, Monitoring by an HIV-trained primary care nurse, and 5 other interventions for HIV Infections. Completed, enrolled 812 participants.

Detailed Summary

The purpose of this study is to determine the effectiveness of several anti-HIV treatment strategies in resource-poor South African communities. The strategies being studied are using specially trained doctors or nurses to administer HIV care.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHIV Infections
Countries--
CollaboratorsNational Institute of Allergy and Infectious Diseases (NIAID)

Timeline

N/ACompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedNov 21, 2005
Enrollment StartJul 1, 2006
Primary CompletionJan 1, 2009
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 20.6 years ago

Interventions

Monitoring by an HIV-trained medical doctorbehavioral

Participants will receive care from an HIV-trained medical doctor

Monitoring by an HIV-trained primary care nursebehavioral

Participants will receive care from an HIV-trained primary care nurse

Efavirenzdrug

600 mg tablet taken orally daily

Lamivudinedrug

150 mg tablet taken orally daily

Lopinavir/Ritonavirdrug

400 mg lopinavir/100mg ritonavir tablet taken orally twice daily

Nevirapinedrug

200 mg tablet taken orally for 14 days before taking a 200 mg tablet orally twice daily

Stavudinedrug

Tablet taken orally daily. Dosage depends on weight.