CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 403 enrolled
Drug / intervention
Rotavirus Vaccine, Live, Oral, Pentavalent +2 morebiological
Likely dose
3 doses of rotavirus vaccine live, oral, pentavalent on Day 1, 28 to 42 days post dose 1 and 28 to 42 days post dose 2AI-extracted
Key inclusion· 1
  • Healthy infant aged 6 through 12 weeks
Key exclusion· 14
  • History of congenital abdominal disorders, intussusception, or abdominal surgery
  • Known or suspected impairment of immunological function
  • Known hypersensitivity to any component of the rotavirus vaccine or INFANRIX Hexa
  • Prior administration of any rotavirus vaccine or oral polio vaccine

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00258154
NCT00258154Phase 3Completed

Safety and Immunogenicity of Concomitant Use of V260 and INFANRIX™ Hexa in Healthy Infants

Merck Sharp & Dohme LLC·interventional·Posted Nov 24, 2005·Updated Oct 6, 2015

In Brief

A Phase 3 clinical trial evaluating Rotavirus Vaccine, Live, Oral, Pentavalent, Comparator: placebo, and 1 other intervention for Rotavirus Disease. Completed, enrolled 403 participants.

Detailed Summary

The study is being conducted to demonstrate that the vaccine to prevent gastroenteritis due to rotavirus may be administered concomitantly with INFANRIX(tm)hexa without impairing the safety and immunogenicity of either vaccine.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedNov 24, 2005
Enrollment StartFeb 1, 2006
Primary CompletionNov 1, 2006
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 20.6 years ago

Interventions

Rotavirus Vaccine, Live, Oral, Pentavalentbiological

3 doses of rotavirus vaccine live, oral, pentavalent on Day 1, 28 to 42 days post dose 1 and 28 to 42 days post dose 2

Comparator: placebobiological

3 doses of placebo to rotavirus vaccine live, oral, pentavalent on Day 1, 28 to 42 days post dose 1 and 28 to 42 days post dose 2

Comparator: Infanrix(tm) Hexabiological

3 doses of oral Infanrix(tm) Hexa on Day 1, 28 to 42 days post dose 1 and 28 to 42 days post dose 2