CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 210 target
Drug / intervention
Paroxetine +2 moredrug
Likely dose
Paroxetine 20 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00261729
NCT00261729N/ACompleted
CompareCT.gov

Prazosin vs. Paroxetine in Combat Stress Symptoms in OIF/OEF Returnees

US Department of Veterans Affairs·interventional·Posted Dec 5, 2005·Updated Dec 3, 2009

In Brief

A clinical study evaluating Paroxetine, Prazosin, and 1 other intervention for Sleep Disorders and Stress Disorders, Post-Traumatic. Completed, enrolled 210 participants across 1 site.

Detailed Summary

Evaluate the efficacy and tolerability of the drug prazosin compared to placebo for combat stress-related nightmares, sleep disturbance and overall function in recently combat-exposed returnees from OIF and OEF. To evaluate the effects of the SSRI paroxetine on behavioral symptoms and overall function in this population.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSleep Disorders, Stress Disorders, Post-Traumatic
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedDec 5, 2005
Enrollment StartJul 1, 2004
Primary CompletionAug 1, 2007
Study CompletionDec 1, 2009
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 20.6 years ago

Interventions

Paroxetinedrug

paroxetine 20 mg

Prazosindrug

Prazosin

placebodrug

placebo capsules