At a glance

ClinicalIndex Comparison Record

Phase 2Completed· 69 enrolled

Drug / intervention

Sertraline +2 moredrug

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00262223

NCT00262223Phase 2Completed

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Combined Treatment for Alcohol-Dependent Individuals With PTSD

New York State Psychiatric Institute·interventional·Posted Dec 6, 2005·Updated Mar 3, 2020

In Brief

A Phase 2 clinical trial evaluating Seeking Safety, Sertraline, and 1 other intervention for Stress Disorders, Post-Traumatic and 2 related conditions. Completed, enrolled 69 participants across 1 site.

Detailed Summary

This treatment intervention trial is designed for men and women with either alcohol misuse (e.g. hazardous or binge drinking) or alcohol use disorders (alcohol abuse or dependence) and comorbid PTSD. Participants will be randomly assigned to one of two treatments (a cognitive behavioral treatment intervention called "Seeking Safety" + Medication ("Zoloft") or Seeking Safety + placebo) and will be evaluated at baseline, at completion of the treatment (12 sessions over 12 weeks), and again at 6 months and 12 months post-treatment.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsStress Disorders, Post-Traumatic, Alcohol Abuse, Substance-Related Disorders

CountriesUnited States

CollaboratorsNational Institute on Alcohol Abuse and Alcoholism (NIAAA)

Timeline

Phase 2CompletedFinished

2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027

First PostedDec 2005

Enrollment StartMay 2006

Primary CompletionJul 2013

TodayJul 2026

First PostedDec 6, 2005

Enrollment StartMay 1, 2006

Primary CompletionJul 1, 2013

TodayJul 2, 2026

Enrollment to primary: 7.2 yearsPosted 20.6 years ago

Interventions

Seeking Safetybehavioral

Seeking Safety cognitive-behavioral treatment intervention for comorbid PTSD and substance use disorders

Sertralinedrug

An anti-depressant medication, selective serotonin reuptake inhibitor (SSRI) type

Pill placebodrug