At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Parallel-Group, 12-Week Study to Assess the Clinically Effective Dose Range of Etoricoxib and to Assess Its Safety and Tolerability in Patients With Rheumatoid Arthritis
In Brief
A Phase 2 clinical trial evaluating etoricoxib, Comparator: placebo, and 1 other intervention for Rheumatoid Arthritis. Completed, enrolled 761 participants.
Detailed Summary
To assess the clinically active dose range of study medication in the treatment of patients with rheumatoid arthritis.
Study Details
Timeline
Interventions
Period I: Arm 1: etoricoxib 10 mg tablet once daily. 12 weeks of treatment.
Period I: Arm 2: etoricoxib 30 mg tablet once daily. 12 weeks of treatment.
Period I: Arm 3: etoricoxib 60 mg tablet once daily. 12 weeks of treatment.
Period I: Arm 4: etoricoxib 90 mg tablet once daily. 12 weeks of treatment.
Period I: Arm 5: Pbo tablet once daily. 12 weeks of treatment.
Period II: Arm 1: etoricoxib 90 mg tablet once daily. 12 weeks of treatment.
Period II: Arm 2: diclofenac 75 mg tablet twice daily. 12 weeks of treatment.