CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 196 enrolled
Drug / intervention
Comparator: atorvastatin +3 moredrug
Likely dose
Comparator: atorvastatin 40mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00276458
NCT00276458Phase 3Completed

A Multicenter., Rand., Double-Blind, Titration Study to Evaluate & Compare the Efficacy & Safety of Ezetimibe Plus Atorvastatin Vs Atorvastatin in Hypercholesterolemic Pts. at Moderately High Risk for CHD Not Adequately Controlled on Atorvastatin 20 Mg

Organon and Co·interventional·Posted Jan 13, 2006·Updated May 13, 2024

In Brief

A Phase 3 clinical trial evaluating Comparator: atorvastatin, Comparator: Placebo, and 2 other interventions for Hypercholesterolemia. Completed, enrolled 196 participants.

Detailed Summary

The purpose of this study is to evaluate and compare the efficacy and safety of ezetimibe plus atorvastatin versus atorvastatin in hypercholesterolemic patients at moderately high risk for coronary heart disease not adequately controlled on atorvastatin 20 mg.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJan 13, 2006
Enrollment StartFeb 1, 2006
Primary CompletionJan 1, 2008
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 20.5 years ago

Interventions

Comparator: atorvastatindrug

Atorvastatin 40mg tablet po qd (by mouth, once a day) for 6 weeks

Comparator: Placebodrug

Atorvastatin 20mg Pbo and ezetimibe 10mg Pbo tablets po qd (by mouth, once a day). for 6 weeks

Comparator: ezetimibedrug

Atorvastatin 20mg and ezetimibe 10mg tablets po qd (by mouth, once a day). for 6 weeks.

Comparator: Placebo.drug

Atorvastatin 40mg Pbo tablets po qd (by mouth, once a day). for 6 weeks.