At a glance

ClinicalIndex Comparison Record

Phase 2Completed· 75 enrolled

Drug / intervention

carboplatin +1 moredrug

Likely dose

docetaxel 75 mgfrom record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00280735

NCT00280735Phase 2Completed

Compare CT.gov

Phase II Trial Exploring the Feasibility of Adjuvant Carboplatin/Docetaxel in Curatively Resected Stage I-IIIA Non-Small Cell Lung Cancer

UNC Lineberger Comprehensive Cancer Center·interventional·Posted Jan 23, 2006·Updated Jul 11, 2017

In Brief

A Phase 2 clinical trial evaluating carboplatin and docetaxel for Lung Cancer. Completed, enrolled 75 participants across 1 site.

Detailed Summary

RATIONALE: Drugs used in chemotherapy, such as carboplatin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving carboplatin together with docetaxel after surgery may kill any tumor cells that remain after surgery. PURPOSE: This phase II trial is studying how well giving carboplatin together with docetaxel works in treating patients with stage I, stage II, or stage III non-small cell lung cancer.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsLung Cancer

CountriesUnited States

CollaboratorsAventis Pharmaceuticals

Timeline

Phase 2CompletedFinished

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027

Enrollment StartMay 2004

First PostedJan 2006

Primary CompletionJul 2011

TodayJul 2026

First PostedJan 23, 2006

Enrollment StartMay 1, 2004

Primary CompletionJul 1, 2011

TodayJul 2, 2026

Enrollment to primary: 7.2 yearsPosted 20.4 years ago

Interventions

carboplatindrug

Carboplatin will be given intravenously,once,every 3 weeks. The carboplatin area under curve (AUC) dose will be calculated using the Calvert Equation 19 as follows: Carboplatin dose (mg) = 6x (GFR + 25)

docetaxeldrug

75 mg/m² intravenously, once, every 3 weeks