CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 55 enrolled
Drug / intervention
Cyclophosphamide +7 moredrug
Likely dose
Cyclophosphamide 300 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00290433
NCT00290433Phase 2Completed

A Phase II Study of the Efficacy of the HCVIDDOXIL Regimen in Patients With Newly Diagnosed Peripheral T Cell Lymphoma

M.D. Anderson Cancer Center·interventional·Posted Feb 13, 2006·Updated Sep 23, 2020

In Brief

A Phase 2 clinical trial evaluating Cyclophosphamide, Mesna, and 6 other interventions for Lymphoma. Completed, enrolled 55 participants across 1 site.

Detailed Summary

The goal of this clinical research study is to learn if treatment with two types of chemotherapy combinations can help to control peripheral T-cell lymphoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLymphoma
CountriesUnited States
CollaboratorsOrtho Biotech, Inc.

Timeline

Phase 2CompletedFinished
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 13, 2006
Enrollment StartSep 1, 2003
Primary CompletionJul 1, 2015
TodayJul 2, 2026
Enrollment to primary: 11.8 yearsPosted 20.4 years ago

Interventions

Cyclophosphamidedrug

Cycle 1: 300 mg/m\^2 by vein Over 3 Hours Twice Daily on Days 1, 2, and 3.

Mesnadrug

Cycle 1: 600 mg/m\^2 by vein Continuous Infusion Over Days 1, 2, and 3.

Vincristinedrug

Cycle 1: 1.4 mg/m\^2 by vein On Day 4 and 11.

Methotrexatedrug

Cycle 1 and 2: 200 mg/m\^2 by vein Over 2 Hours on Day 1, followed by 800 mg/m\^2 IV Over 22 Hours on Day 1.

Ara-Cdrug

Cycle 1 and 2: 3 Gm/m\^2 Over 2 Hours Twice Daily On Days 2 and 3.

Dexamethasonedrug

Cycle 1: 40 mg by vein or by mouth daily on Days 1-4 and 11-14.

G-CSFdrug

Cycle 1 and 2: 300 or 480 mcg subcutaneously 24 hours after end of Day 4 vincristine.

Doxildrug

Cycle 1: 25 mg/m\^2 by vein Over 1 Hour on Day 2.