At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 30 enrolled
Drug / intervention
Caffeinol +1 moredrug
Likely dose
Caffeinol 9mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Combined Neuroprotective Modalities Coupled With Thrombolysis in Acute Ischemic Stroke: A Pilot Study of Caffeinol and Mild Hypothermia
The University of Texas Health Science Center, Houston·interventional·Posted Mar 6, 2006·Updated May 3, 2011
In Brief
A Phase 2 clinical trial evaluating Caffeinol and hypothermia for Acute Ischemic Stroke. Completed, enrolled 30 participants across 1 site.
Detailed Summary
Caffeinol is a combination of caffeine and alcohol. The amount given is about the same as 1-2 glasses of wine and 3-4 cups of coffee. The patient receives a one time dose given over two hour while being cooled to 34.5 C.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Ischemic Stroke
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartFeb 2003
First PostedMar 2006
Primary CompletionJan 2009
Study CompletionAug 2009
TodayJul 2026
First PostedMar 6, 2006
Enrollment StartFeb 1, 2003
Primary CompletionJan 1, 2009
Study CompletionAug 1, 2009
TodayJul 2, 2026
Enrollment to primary: 5.9 yearsPosted 20.3 years ago
Interventions
Caffeinoldrug
Infusion of caffeinol (9mg/kg caffeine + 0.4g/kg ethanol) over 2 hours.
hypothermiaprocedure
External or internal cooling for 24 hours and rewarming over 12 hours.