CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 97 enrolled
Drug / intervention
MaZiRenWan (MZRW) Low dose +2 moredrug
Likely dose
MaZiRenWan (MZRW) Low dose 2.5gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00299975
NCT00299975Phase 2Completed
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A Randomized Controlled Trial of Chinese Herbal Medicine in Three-dose Regimen for the Treatment of Functional Constipation

Hong Kong Baptist University·interventional·Posted Mar 7, 2006·Updated Apr 24, 2015

In Brief

A Phase 2 clinical trial evaluating MaZiRenWan (MZRW) Low dose, MaZiRenWan (MZRW) Median dose, and 1 other intervention for Constipation. Completed, enrolled 97 participants across 1 site.

Detailed Summary

Functional constipation (FC) is common with 14.3% estimated prevalence in Hong Kong, but treatment for this condition in conventional medicine is suboptimal. Complementary and alternative medicines, especially Chinese herbal medicine (CHM) are used frequently by patients with FC, but there is little research evidence about these commonly used CHM. The purpose of the study is evaluate the efficacy and safety of CHM, as well as determining the optimal dosage.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsConstipation
CountriesChina
Collaborators--

Timeline

Phase 2CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 7, 2006
Enrollment StartOct 1, 2006
Primary CompletionAug 1, 2007
Study CompletionOct 1, 2007
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 20.3 years ago

Interventions

MaZiRenWan (MZRW) Low dosedrug

Dissolved MaZiRenWan (MZRW) granule (2.5g/sachet) in 150 ml hot water, take orally twice daily for 8 weeks

MaZiRenWan (MZRW) Median dosedrug

Dissolved MaZiRenWan (MZRW) granule (5.0g/sachet) in 150 ml hot water, take orally twice daily for 8 weeks

MaZiRenWan (MZRW) High dosedrug

Dissolved MaZiRenWan (MZRW) granule (7.5g/sachet) in 150 ml hot water, take orally twice daily for 8 weeks