At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 12 enrolled
Drug / intervention
voriconazoledrug
Likely dose
Voriconazole 400 mg orally twice daily (loading) followed by 200 mg orally twice daily (maintenance)AI-extracted
Key inclusion· 2
- ✓Willing and able to provide informed consent
- ✓Willing and able to be confined at the Clinical Research Unit as required by the protocol
Key exclusion· 1
- ✕Any condition affecting drug absorption
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Assessment Of Voriconazole Penetration Into The Brain By Fluorine-Magnetic Resonance Spectroscopy
In Brief
A Phase 4 clinical trial evaluating voriconazole for Infections, Fungal. Completed, enrolled 12 participants across 1 site.
Detailed Summary
To determine the amount of voriconazole in the brain after 2 loading doses and 3 maintenance doses over 3 days and compare it to the amount of voriconazole in the plasma.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsInfections, Fungal
CountriesUnited States
CollaboratorsMcLean Hospital. Belmont, MA.
Timeline
Phase 4CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 2006
Enrollment StartMar 2007
Primary CompletionAug 2008
TodayJul 2026
First PostedMar 9, 2006
Enrollment StartMar 1, 2007
Primary CompletionAug 1, 2008
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 20.3 years ago
Interventions
voriconazoledrug
Multiple oral doses of voriconazole at 400 mg loading twice daily followed by 200 mg maintenance twice daily