At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Treatment of Adrenocortical Tumors With Surgery Plus Lymph Node Dissection and Multiagent Chemotherapy: A Groupwide Phase III Study
In Brief
A Phase 3 clinical trial evaluating Cisplatin, Conventional Surgery, and 5 other interventions for Stage I Adrenal Cortical Carcinoma AJCC v7 and 3 related conditions. Completed, enrolled 78 participants across 91 sites in 4 countries.
Detailed Summary
This phase III clinical trial is studying how well cisplatin-based chemotherapy and/or surgery works in treating young patients with stage I, stage II, stage III or stage IV adrenocortical cancer. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. Giving chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving it after surgery may kill any tumor cells that remain after surgery.
Study Details
Timeline
Interventions
Given IV
Patients undergo surgery
Given IV
Given IV
Given subcutaneously
Given orally
Given subcutaneously