At a glance
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Intravaginal LACTIN-V for Prevention of Recurrent Urinary Tract Infections
In Brief
A Phase 2 clinical trial evaluating Lactin-V and Placebo for Urinary Tract Infection. Completed, enrolled 100 participants across 1 site.
Detailed Summary
Recurrent urinary tract infections (RUTIS) continue to be a major health problem in women and are now complicated by increasing antibiotic resistance. New preventive approaches are needed. Because most women with RUTI lack the normal protective Lactobacillus (LB) in their vaginal flora, we hypothesized that restoration of LB would reduce RUTIS. In this trail, women with recent UTI are randomized to receive either LB or placebo vaginal capsules and are followed for side effects, for colonization with LB and for occurrence of RUTI over hte next four months.