CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 404 enrolled
Drug / intervention
BG00002 (natalizumab)biological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00306592
NCT00306592Phase 3Completed

An Open-Label, Multicenter, Extension Study to Evaluate the Safety and Tolerability of Natalizumab Following Re-Initiation of Dosing in Multiple Sclerosis Subjects Who Have Completed Study C-1801, C-1802, or C-1803 and a Dosing Suspension Safety Evaluation

Biogen·interventional·Posted Mar 24, 2006·Updated Mar 21, 2017

In Brief

A Phase 3 clinical trial evaluating BG00002 (natalizumab) for Multiple Sclerosis, Relapsing-Remitting. Completed, enrolled 404 participants across 63 sites in 2 countries.

Detailed Summary

The primary objectives of this study are to further evaluate the safety of natalizumab (Tysabri®) monotherapy by evaluating the risk of hypersensitivity and immunogenicity following re-exposure to natalizumab, and to confirm the safety of switching to natalizumab from interferon beta (IFN-β), glatiramer acetate (GA), or other multiple sclerosis (MS) therapies.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States

Timeline

Phase 3CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 24, 2006
Enrollment StartMar 1, 2006
Primary CompletionDec 1, 2007
Study CompletionFeb 1, 2008
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 20.3 years ago

Interventions

BG00002 (natalizumab)biological