CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 351 enrolled
Drug / intervention
GSK Biologicals' 10-valent pneumococcal conjugate vaccine. +2 morebiological
Likely dose
GSK 10-valent pneumococcal conjugate vaccine, intramuscular injection, 3 or 4 doses on 2-4-11 months of age schedule (or 2-3-4-11 months of age schedule)AI-extracted
Key inclusion· 4
  • Male or female infant between 8 and 16 weeks of age (56-120 days) at first vaccination
  • Born after gestation period of 36 to 42 weeks
  • Free of obvious health problems by medical history and clinical examination before study entry
  • Parents/guardians can and will comply with protocol requirements
Key exclusion· 10
  • Previous vaccination against diphtheria, tetanus, pertussis, polio, hepatitis B, Haemophilus influenzae type b, and/or S. pneumoniae
  • History of diphtheria, tetanus, pertussis, hepatitis B, polio, Haemophilus influenzae type b disease, and/or invasive pneumococcal diseases
  • History of allergic disease or reactions likely to be exacerbated by any vaccine component
  • History of neurologic disorders or seizures

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00307034
NCT00307034Phase 3Completed

An Open, Randomized, Phase IIIa Study to Evaluate the Safety and Immunogenicity of GSK Biologicals' 10-valent Pneumococcal Conjugate Vaccine, When Administered Intramuscularly According to a 2-4-11 Months Vaccination Schedule

GlaxoSmithKline·interventional·Posted Mar 27, 2006·Updated Jun 8, 2018

In Brief

A Phase 3 clinical trial evaluating GSK Biologicals' 10-valent pneumococcal conjugate vaccine., Infanrix hexa., and 1 other intervention for Infections, Streptococcal. Completed, enrolled 351 participants across 8 sites in 4 countries.

Detailed Summary

Assess immuno, reacto of the 10-valent pneumococcal vaccine after 2 doses (2, 4 months of age) and after the complete 2, 4, 11 months schedule when co-administered with DTPa-HBV-IPV/Hib or DTPa-IPV/Hib (according to national recommendations)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesDenmark, Norway, Slovakia, Sweden
Collaborators--

Timeline

Phase 3CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 27, 2006
Enrollment StartJan 1, 2006
Primary CompletionJan 1, 2007
Study CompletionJan 25, 2007
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 20.3 years ago

Interventions

GSK Biologicals' 10-valent pneumococcal conjugate vaccine.biological

Intramuscular injection, 3 or 4 doses (2-4-11 or 2-3-4-11 months of age schedule).

Infanrix hexa.biological

Intramuscular injection, 3 doses (2-4-11 months of age schedule).

Infanrix-IPV/Hib.biological

Intramuscular injection, 3 doses (2-4-11 months of age schedule).