At a glance

ClinicalIndex Comparison Record

Phase 3Completed· 1,020 enrolled

Drug / intervention

Centrum +1 moredietary

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00309387

NCT00309387Phase 3Completed

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Collaborative Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS)

National Eye Institute (NEI)·interventional·Posted Mar 31, 2006·Updated May 6, 2013

In Brief

A Phase 3 clinical trial evaluating Centrum and Placebo for Cataract. Completed, enrolled 1,020 participants across 1 site.

Detailed Summary

The Collaborative Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS) is a 13-year study designed primarily to evaluate the safety and efficacy of a vitamin-mineral supplement (Centrum) containing recommended daily-allowance dosage (RDA) in preventing age-related cataract or delaying its progression in participants with early or no cataract at baseline.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsCataract

CountriesItaly

Collaborators--

Timeline

Phase 3CompletedFinished

199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027

Enrollment StartMay 1995

First PostedMar 2006

Primary CompletionMay 2007

TodayJul 2026

First PostedMar 31, 2006

Enrollment StartMay 1, 1995

Primary CompletionMay 1, 2007

TodayJul 2, 2026

Enrollment to primary: 12 yearsPosted 20.3 years ago

Interventions

Centrumdietary

Multivitamin/mineral supplement containing US RDA levels of nutrients. 1 tablet a day for the expected duration of follow-up (on average 10 yrs).

Placeboother

placebo tablets manufactured to mimic Centrum tablets.