CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 204 enrolled
Drug / intervention
CP-751,871 +4 moredrug
Likely dose
CP-751,871 20 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00313781
NCT00313781Phase 2Completed
CompareCT.gov

A Phase 2, Randomized, Non-Comparative, Two-Arm Open Label, Multiple-Center Study Of CP-751,871 In Combination With Docetaxel/Prednisone In Chemotherapy- Naive (Arm A) And Docetaxel/Prednisone Refractory (Arm B) Patients With Hormone Insensitive Prostate Cancer

Pfizer·interventional·Posted Apr 12, 2006·Updated Apr 11, 2013

In Brief

A Phase 2 clinical trial evaluating CP-751,871, docetaxel, and 1 other intervention for Prostatic Neoplasms. Completed, enrolled 204 participants across 18 sites in 6 countries.

Detailed Summary

To test the efficacy of CP-751,871 combined with docetaxel and prednisone in the treatment of prostate cancer that is refractory to hormone therapy

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsProstatic Neoplasms
CountriesCanada, Germany, Spain, Switzerland, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedApr 12, 2006
Enrollment StartMay 1, 2006
Primary CompletionApr 1, 2011
Study CompletionDec 1, 2011
TodayJul 2, 2026
Enrollment to primary: 4.9 yearsPosted 20.2 years ago

Interventions

CP-751,871drug

CP-750,871 is administered intravenously at a dose of 20 mg/kg on day 1 of each 21-day cycle (for patient convenience and logistical management, the dose of CP-751,871 may be deferred up to 7 days).

docetaxeldrug

Docetaxel is administered IV on day 1 of each 21-day cycle, at a dose of 75 mg/m2.

prednisonedrug

Prednisone is administered at a dose of 5 mg twice daily.

docetaxeldrug

Docetaxel is administered IV on day 1 of each 21-day cycle, at a dose of 75 mg/m2.

prednisonedrug

Prednisone is administered at a dose of 5 mg twice daily.