CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 365 enrolled
Drug / intervention
Saxagliptin +5 moredrug
Likely dose
Saxagliptin 2.5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00316082
NCT00316082Phase 3Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy and Safety of Saxagliptin as Monotherapy With Titration in Subjects With Type 2 Diabetes Who Have Inadequate Glycemic Control With Diet and Exercise

AstraZeneca·interventional·Posted Apr 20, 2006·Updated Apr 29, 2015

In Brief

A Phase 3 clinical trial evaluating Saxagliptin, Placebo, and 1 other intervention for Diabetes. Completed, enrolled 365 participants across 74 sites in 4 countries.

Detailed Summary

The purpose of this trial is to understand if saxagliptin is more effective than placebo as a treatment for type 2 diabetic subjects who are not controlled with diet and exercise

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDiabetes
CountriesIndia, Russia, Taiwan, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedApr 20, 2006
Enrollment StartJun 1, 2006
Primary CompletionNov 1, 2007
Study CompletionNov 1, 2008
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 20.2 years ago

Interventions

Saxagliptindrug

Coated tablets, Oral, 2.5 mg, QAM, Daily (6 months ST, 12 months LT)

Saxagliptindrug

Coated tablets, Oral, 2.5 mg titrated to 5mg, QAM, Daily (6 months ST, 12 months LT)

Saxagliptindrug

Coated tablets, Oral, 5mg, QAM, Daily, (6 months ST, 12 months LT)

Saxagliptindrug

Coated tablets, Oral, 5mg QPM, Daily (6 months ST, 12 months LT)

Placebodrug

Coated tablets, Oral, 0mg, Daily (6 months ST, 12 months LT)

metformindrug

Tablets, Oral, 500-2000 mg, as needed (12 months LT)