CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 14 enrolled
Drug / intervention
Divalproex Sodium Extended-Release Tabletsdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00318929
NCT00318929N/ACompleted
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Tolerability and Efficacy of Depakote-ER in the Elderly

Virginia Commonwealth University·interventional·Posted Apr 27, 2006·Updated Feb 5, 2018

In Brief

A clinical study evaluating Divalproex Sodium Extended-Release Tablets for Elderly and 2 related conditions. Completed, enrolled 14 participants across 1 site.

Detailed Summary

There is a bimodal distribution to the new onset seizures with one peak occurring in the very young and the second peak occurring in persons over age 65 years. The presentation of seizures in the elderly may vary from that of younger patients and the diagnosis may be confused with other conditions such as transient ischemic attacks. However, the consequences of epilepsy in the elderly can be severe leading to impaired cognition, increased falls, and a decreased quality of life. The treatment of epilepsy may be complicated by pharmacokinetic and pharmacodynamic changes occurring in the elderly.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsElderly, Epilepsy, Seizures
CountriesUnited States
CollaboratorsAbbott

Timeline

N/ACompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedApr 27, 2006
Enrollment StartApr 1, 2006
Primary CompletionJan 1, 2008
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 20.2 years ago

Interventions

Divalproex Sodium Extended-Release Tabletsdrug

Once a day dosing