CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 198 enrolled
Drug / intervention
Aripiprazole +1 moredrug
Likely dose
Aripiprazole 5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00320671
NCT00320671Phase 4Completed
CompareCT.gov

Preventing Morbidity in First Episode Schizophrenia, Part II

Northwell Health·interventional·Posted May 3, 2006·Updated Sep 8, 2016

In Brief

A Phase 4 clinical trial evaluating Aripiprazole and Risperidone for Schizophrenia. Completed, enrolled 198 participants across 1 site.

Detailed Summary

This 52 week long study evaluates the effectiveness of aripiprazole versus risperidone in treating people with first-episode schizophrenia. Patients who do not improve with these medications receive clozapine as their third medication trial.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSchizophrenia
CountriesUnited States
CollaboratorsNational Institute of Mental Health (NIMH)

Timeline

Phase 4CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 3, 2006
Enrollment StartDec 1, 2005
Primary CompletionDec 1, 2014
Study CompletionDec 1, 2015
TodayJul 2, 2026
Enrollment to primary: 9 yearsPosted 20.2 years ago

Interventions

Aripiprazoledrug

The dosage for aripiprazole will be 5 mg to 30 mg per day in capsule form. The dose of aripiprazole will be based on the participant's clinical improvement and side effects, which will be evaluated weekly for the first 4 weeks and then every 2 weeks until the 12th week and then monthly until study end.

Risperidonedrug

The dosage for risperidone will be 1 mg to 6 mg per day in capsule form. The dose of risperidone will be based on the participant's clinical improvement and side effects, which will be evaluated weekly for the first 4 weeks, then every 2 weeks until the 12th week, and then monthly until the study end.