CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 57 enrolled
Drug / intervention
Active Breathing Coordinatordevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00321048
NCT00321048N/ACompleted
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Spect Analysis of Cardiac Perfusion Changes After Whole Breast/Chest Wall Radiation Therapy With Active Breathing Coordinator

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins·interventional·Posted May 3, 2006·Updated Feb 28, 2025

In Brief

A clinical study evaluating Active Breathing Coordinator for Breast Neoplasms and 2 related conditions. Completed, enrolled 57 participants across 1 site.

Detailed Summary

Cardiac perfusion changes have been seen after whole breast / chest wall irradiation for breast cancer. The Active Breathing Coordinator (ABC) device theoretically decreases radiation exposure to the heart during radiation for breast cancer. In this trial cardiac perfusion changes or lack thereof will be quantified in women treated with radiation for breast cancer while using the ABC device. The control group of the study will consist of patients randomized to radiation therapy without the ABC device.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBreast Neoplasms, Carcinoma, Ductal, Adenocarcinoma
CountriesUnited States
CollaboratorsBreast Cancer Research Foundation

Timeline

N/ACompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 3, 2006
Enrollment StartJun 1, 2006
Primary CompletionJan 1, 2010
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 20.2 years ago

Interventions

Active Breathing Coordinatordevice

A SPECT scan will be used to determine if the active breathing device reduces radiation toxicities.