CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 142 enrolled
Drug / intervention
Background ARVs +2 moredrug
Likely dose
enfuvirtide [Fuzeon] 90mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00326963
NCT00326963Phase 4Completed

A Multicenter, Open-label Study Evaluating the Safety and Efficacy of a New Protease Inhibitor (Darunavir) With Fuzeon® (Enfuvirtide) Plus Background Antiretroviral Regimen in HIV-1 Infected, Triple-class Treatment-experienced Patients

Hoffmann-La Roche·interventional·Posted May 17, 2006·Updated Aug 16, 2016

In Brief

A Phase 4 clinical trial evaluating Background ARVs, PI, and 1 other intervention for HIV Infections. Completed, enrolled 142 participants across 38 sites in 2 countries.

Detailed Summary

This single arm study will evaluate the efficacy, safety and tolerability of a new investigational protease inhibitor (PI) plus background antiretrovirals plus Fuzeon (90mg sc bid) in HIV-1 infected, triple-class treatment-experienced, Fuzeon-naive adults. The new investigational PI will be administered according to the procedures of the early access program in which the patient is enrolled. The anticipated time on study treatment is 3-12 months, and the target sample size is approximately 120 individuals.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHIV Infections
CountriesAustralia, United States
CollaboratorsTrimeris

Timeline

Phase 4CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 17, 2006
Enrollment StartMar 1, 2006
Primary CompletionApr 1, 2007
Study CompletionMay 1, 2007
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 20.1 years ago

Interventions

Background ARVsdrug

As prescribed

PIdrug

As prescribed

enfuvirtide [Fuzeon]drug

90mg sc bid